USPTO Patents Application 09544084

FORM PTO-1449
(Modified)

U.S. Department of Commerce
Patent and Trademark Office

INFORMATION DISCLCWMffiW^TEMENT BY APPLICANT

(Use Several Sheets If Necessary)

(37 CFR§ 1.98(b))

Attorney Docket No.: Conlinco-04286

MAY 2 3 fl)0l

Serial No.: 09/544,084

Applicant: Asgeir Saebo et al.

IKHCtNIBt 1600/2900

Filing Date: 04/06/2000

Group Art Unit: 1617

U.S. PATENT DOCUMENTS

Pyq mi r\ f*r
OAal I11IICI

Initials

Cite*

No.

<5prin1 / Patent
Number

Issue Date

Applicant / Patentee

Class

Subclass

Filing Date

1

5,585,400

112/17/96

Cook, et al.

514

560

02/27/96

2

5,674,901

09/30/97

Cook, et al.

246

452

11/06/95

$ I/O

3

5,430,066

07/04/95

Cook, et al

514

558

04/29/92

4

5,554,646

09/10/96

Cook, et al.

514

560

08/29/94

5

5,428,072

06/27/95

Cook, et al.

514

560

01/22/93

6

4,164,505

08/14/79

Krajca

260

405.6

07/08/77

7

5,856,149

01/05/99

Pariza et al.

435

134

12/03/96

8

5,814,663

09/29/98

Cook et al.

514

560

08/28/96

9

5,804,210

09/08/98

Cook et al.

424

440

08/07/96

10

5,827,885

10/27/98

Cook et al

514

558

08/18/97

11

5,851,572

12/22/98

Cook et al.

426

2

04/25/97

12

5,855,917

01/05/99

Cook et al

424

502

12/04/96

13

2,242,230

5/20/1941

Bun-

260

398

06/22/38

14

2,350,583

06/06/1944

Bradley

260

195.6

02/08/41

15

3,162,658

12/22/1964

12/1964

260

405.6

11/21/60

16

3,278,567

10/11/1966

Rathjen et al

260

405.6

01/19/65

17

3,729,379

4/24/1973

Emken

195

30

08/31/71

18

5,017,614

5/21/1991

Pariza et al.

514

558

2/17/89

19

5,070,104

12/3/1991

Pariza et al.

514

549

2/2/90

20

5,208,356

5/4/1993

Pariza et al.

554

79

3/3/91

21

5,725,873

3/10/1998

Cook et al.

424

442

7/22/96

22

5,760,082

6/2/1998

Cook et al.

514

560

6/7/96

23

5,760,083

6/2/1998

Cook et al.

514

560

8/7/96

24

4,381,264

4/26/1983

Struve

260

405.6

5/20/81

25

5,986,116

11/16/99

Iwata et al

554

126

10/24/97

26

5,885,594

03/23/99

Nilsen et al.

424

401

03/27/97

27

5,468,887

11/21/91

Gupta

554

169

03/13/93

28

5,288,619

02/22/94

Brown et al.

435

134

06/22/92

29

6,015,833

01/18/00

Saebo et al

514

558

03/17/98

Examiner: <2, , [ /^/^ ^

Date Considered: *? ' ° ^ ° /

EXAMINER: Initial citation considered. Draw line through citation if not in conformance and not considered. Include copy of this form
with next communication to applicant.

RECEWeii

Sheet 2 of 3

t fW fc i ^ — g#

FORM PTO-1449 V- U.S. Department of Commerce
(Modified) Patent and Trademark Office

INFORMATION DISCb&ffijfijSwTEMENT BY APPLICANT

(Use Several Sheets If Necessary)

(37 CFR§ 1.98(b))

Attorney Docket No.: Conlinco-04286

IC'wIlOUHIUI .www—

Applicant: Asgeir Saebo et al

Filing Date: 04/06/2000

Group Art Unit: 1617

FOREIGN PATENTS OR PUBLISHED FOREIGN PATENT APPLICATIONS

Document
Number

Publication Date

Country / Patent Office

Class

Subclass

Translation

Vpc
I Co

No

30

WO 97/46230

12/1 1/97

PCT

Aul K.

31

779,033 Al

6/1 8/97

EP

A23D

y/uu

32

WO 98/05318

2/12/98

PCT

A61K

31/20

33

WO 98/05319

2/12/98

PCT

A C 1 V

AolK.
A23K

1/16

34

WO 97/46118

12/11/97

PCT

A23D
A23C

7/00
9/152

35

WO 97/18320

05/22/97

PCT

A T5

A23L
A61K

36

WO 98/49129

PCT

37

WO 96/34855

11/7/96

PCT

C07D
A61K
C07C

209/28
31/23
69/587

38

WO 97/37546

10/16/97

PCT

A23D
CUB

9/05
15/00

39

WO 96/38137

12/05/96

PCT

A61K
A23C
A23L

9

— J

40

558,881

GB

OTHER DOCUMENTS (Including Author, Title, Date, Relevant Pages, Place of Publication)

41

Cowan, "Isomerization and Trans-Esterifiation," JAOCS 72:492-99 (1950)

f

42

Christie et al, "Isomers in Commercial Samples of Conjugated Linoleic Acid," JAOCS 74 (11): 1231 (1997)

43

Kepler et al, J. Biol Chem. 241:1350-54 (1966)

-f-

44

W. Parodi, J. Nutr. 127(6): 1055-60 (1997)

45

Belury, "Conjugated Dienoic Linoleate: A Polyunsaturated Fatty Acid with Unique Chemoprotective Properties," Nut. /?ev.53(4):83-9 (1995)

46

Ha et al. t Cancer Res., 50:1097 (1991)

47

Birt etal, Cancer Res., 52:2035-s (1992)

48

Ip, Am. J. Clin. Nutr. 66(6):1523s (1997)

49

Sehat et al, Lipids 33(2):217-21 (1998)

50

Jie, et al, "High-Resolution Nuclear Magnetic Resonance Spectroscopy - Amplification to Fatty Acids and Triacylglycerols," Lipids 32
(10): 1019-34 (1997)

51

Scholfield and Koritalia, "A Simple Method for Preparation of Methyl trans- 10,cis- 12 Octadecadienoate," JOACS 47(8):303 (1970)

-t-

52

Ron Udell, Information About Conjugated Linoleic Acid, published by Soft Gel Technologies Incorporated

53

Sugano et al, "Conjugated Linoleic Acid Modulates Tissue Levels of Chemical Mediators and Immunoglobulins in Rats," Lipids, 33(5):521-
27 (1998)

Examiner: *y* * L^-^_^"~ >f

Date Considered: ' 2^> — *>/

U

EXAMINER: Initial citation considered. Draw line through citation if not in conformance and not considered. Include copy of this form
with next communication to applicant.

Sheet 3 of 3

FORM PTO- 1449 \ g U.S. Department of Commerce
(Modified) V ^ & Patent and Trademark Office

INFORMATION 0>^^)&Uffl^<\TEMENT BY APPLICANT
(Use S&Vu HrTlICets If Necessary)

(37 CFR§ 1.98(b))

Attorney Docket No.: Conlinco-04286

Serial No.: 09/544,084

Applicant: Asgeir Saebo et ai

Filing Date: 04/06/2000

Group Art Unit: 1617

OTHER DOCUMENTS (Including Author, Title, Date, Relevant Pages, Place of Publication)

54

Haraldsson et ai, Acta Chem Scanned 45:7 73 (1991)

55

Chin et ai, J. Nutrition 124:694 (1994)

56

Matreya Catalog, 1997, pp. 33-34

57

Selin CLA Product Literature, 1/97

58

Hudtwalcker & Co. AS Technical Data Sheet, exact publication date unknown

59

Lipid Technology Newsletter, Peter J. Barnes, Ed., Vol. 4, No. 5, pp 85-86 (October, 1998)

60

Natural Lipids Ltd. AS Technical Data Sheet, 1/20/97

61

Theil et ai, "Conjugated Linoleic Acid Improves Performance and Body Composition in Swine," Iowa State University,Midwest Animal
Sciences Meeting, Abstract 127:61 (1998)

62

Quinn et ai, "A Comparison of Modified Tall Oil and Conjugated Linoleic Acid on Growing-Finishing Pig Growth Performance and
Carcass Characteristics," Kansas State University and Lonza, Inc., Midwest Animal Sciences Meeting, Abstracat 128:61 (1998)

63

Dugan et ai, "The Effect of Conjugated Linoleic Acid on Fat to Lean Repartitioning and Feed Conversion in Pigs," Canadian Journal of
Animal Science 77:723-725 (1997)

64

Shantha et ai t "Conjugated Linoleic Acid Concentrations in Processed Cheese Containing Hydrogen Donors, Iron and Dairy - Based
Additives," Food Chemistry 47:257-261 (1993)

65

Bradley et ai, "Alkali-Induced Isomerization of Drying Oils and Fatty Acids," Ind. Eng. Chem. 34(2):237-242 (1942)

66

Jie et ai, "Synthesis and Nuclear Magnetic Resonance Properties of All Geometrical Isomers of Conjugated Linoleic Acids," Lipids
32(10):1041-1044 (1997)

67

Arcos et ai, "Rapid Enzymatic Production of acylglycerols from conjugated linoleic acid and glyerol in the solvent-free system,"
Biotechnology Letters 20:617 (1998)

68

Holman et ai, "Unusual Isomeric Polyunsaturated Fatty Acids in Liver Phospholipids of Rats Fed Hydrogenated Oil," PNAS 88:4830-34
(1991)

69

Radlove et ai, "Catalytic Isomerization of Vegetable Oils," Ind. Eng. Chem. 38(10):997-1002 (1946)

70

Sebedio et ai, "Linoleic Acid Isomers in Heat Treated Sunflower Oils," JAOCS 65(3):362-366 (1988)

71

Sebedio et ai, "Metabolites of Conjugated Isomers of Linoleic Acid (CLA) in the Rat," Biochem. Biophys. Acta 1345:5-10 (1997)

72

Chin et ai, "Dietary Sources of Conjugated Dienoic Isomers of Linoleic Acids, a Newly Recognized Class of Anticarcinogens," J. Food.
Comp. Anal. 5:185-197 (1992)

.73

Park et ai, "Effect of Conjugated Linoleic Acid on Body Composition in Mice," Lipids 32(8):853-58 (1997)

74

Berdeau et ai, "A Simply Method of Preparation of Methyl trans-\0, cis-\2- and cis-9, trans- 1 1-Octadecadienoates from Methyl Linoleate,"
JAOCS 75:1749-1755 (1998)

41

EXAMINER: Initial citation considered. Draw line through citation if not in conformance and not considered. Include copy of this form
with next communication to applicant.